A family of proton-gated sodium channels that are primarily expressed in neuronal tissue. They are AMILORIDE-sensitive and are involved in the signaling of a variety of neurological stimuli, most notably that of pain in response to acidic conditions.

Synonyms: Channel, Acid-Sensing Ion, Acid-Sensing Ion Channel, Ion Channel, Acid-Sensing, Channel, Proton-Gated Sodium, Acid-Sensing Ion Channels, Acid Sensing Ion Channels, Proton Gated Sodium Channel, ASIC Channel, 0, Proton Gated Sodium Channels, Sodium Channel, Proton-Gated, Proton-Gated Sodium Channel, Proton-Gated Sodium Channels, Sodium Channels, Proton-Gated, Acid Sensing Ion Channel