A secreted protein of approximately 131 amino acids that is related to AGOUTI SIGNALING PROTEIN and is also an antagonist of MELANOCORTIN RECEPTOR activity. It is expressed primarily in the HYPOTHALAMUS and the ADRENAL GLAND. As a paracrine signaling molecule, AGRP is known to regulate food intake and body weight. Elevated AGRP has been associated with OBESITY.
Synonyms: 0, AGRP Protein, Agouti Related Protein, AGRT Protein, Agouti-Related Protein
Instance information
comment
2008; AGOUTI-RELATED PROTEIN was indexed under INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS 1997-2007 ,2008 (1997)
identifier
D054369