A family of membrane-anchored glycoproteins that contain a disintegrin and metalloprotease domain. They are responsible for the proteolytic cleavage of many transmembrane proteins and the release of their extracellular domain.

Synonyms: ADAM (A Disintegrin and Metalloprotease) Proteins, A Disintegrin and Metalloprotease Proteins, EC 3.4.24.-, ADAM Proteins

Instance information

comment

2006

identifier

D051722

Instance relations