One of the BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS that is synthesized as a membrane-bound protein in the ENDOPLASMIC RETICULUM. In response to endoplasmic reticulum stress it translocates to the GOLGI APPARATUS. It is activated by PROTEASES and then moves to the CELL NUCLEUS to regulate GENETIC TRANSCRIPTION of GENES involved in the unfolded protein response.
Synonyms: 0, Activating Transcription Factor 6, ATF6 Transcription Factor, Transcription Factor, ATF6
Instance information
comment
2006(1997) ,2006; ACTIVATING TRANSCRIPTION FACTOR 6 was indexed under DNA-BINDING PROTEINS & TRANSCRIPTION FACTORS 1997-2005
identifier
D051702