A membrane-bound or cytosolic enzyme that catalyzes the synthesis of CYCLIC ADP-RIBOSE (cADPR) from nicotinamide adenine dinucleotide (NAD). This enzyme generally catalyzes the hydrolysis of cADPR to ADP-RIBOSE, as well, and sometimes the synthesis of cyclic ADP-ribose 2' phosphate (2'-P-cADPR) from NADP.

EC 3.2.2.5

Synonyms: 2'-P-ADPR Cyclase, cADPR Hydrolase, ADP-ribose Hydrolase, Cyclic, Cyclase, ADP-ribosyl, 2'-Phospho-adenosine Diphosphate Ribose Cyclase, Cyclic ADP-ribose Hydrolase, ADP-ribosyl Cyclase, Cyclase, ADP Ribose, ADP ribosyl Cyclase, EC 3.2.2.6, EC 3.2.2.5, 2' Phospho adenosine Diphosphate Ribose Cyclase, Hydrolase, Cyclic ADP-ribose, Cyclic ADP ribose Hydrolase, EC 3.2.2.-, 2' P ADPR Cyclase, Cyclase, 2'-P-ADPR, Adenosine Diphosphate Ribose Cyclase, ADPR Cyclase, Hydrolase, cADPR, Cyclase, ADPR, ADP Ribose Cyclase, Ribose Cyclase, ADP