Enzymes that transfer the ADP-RIBOSE group of NAD or NADP to proteins or other small molecules. Transfer of ADP-ribose to water (i.e., hydrolysis) is catalyzed by the NADASES. The mono(ADP-ribose)transferases transfer a single ADP-ribose. POLY(ADP-RIBOSE) POLYMERASES transfer multiple units of ADP-ribose to protein targets, building POLY ADENOSINE DIPHOSPHATE RIBOSE in linear or branched chains.
An enzyme that catalyze the transfer of ADP-RIBOSE from NAD+ to an amino acid residue in a specific protein substrate. This reaction is catalyzed by both mono(ADP-ribose) transferases as well as POLY(ADP-RIBOSE) POLYMERASES. When the term NAD+ ADP-Ribosyltransferase refers to EC 2.4.2.30 it is referring to POLY(ADP-RIBOSE) POLYMERASES.
Enzymes that catalyze the transfer of one ADP-ribose moiety from NAD+ to an amino acid residue in specific protein substrates. This reaction is catalyzed by prokaryotic and eukaryotic enzymes. Mono-ADP-ribosylation is a mechanism of action common to several bacterial toxins.
An enzyme that catalyzes the transfer of the ADP-ribose moiety from NAD+ or NADP+ to specific protein substrates with arginine, arginine-type compounds, agmatine, or guanidine as acceptors. This mono-ADP-ribosylation reaction is the mechanism of action common to several bacterial toxins affecting profound changes in cellular metabolism, such as activation of adenylate cyclase, regulation of protein synthesis at the level of elongation factor 2, and ion transport across biological membranes.
Synonyms: NADP Arginine ADP Ribosyltransferase, ADP-Ribosyltransferase, ART Transferase, ADPRTs, NAD ADP-Ribosyltransferase, ARTases, EC 2.4.2.31, ADP-Ribosyltransferase, NAD-Agmatine, Transferases, ART, ADP-Ribosyltransferase, NAD, ADP Ribose Transferase, Transferase, ART, Ribose Transferase, ADP, NADP-Arginine ADP-Ribosyltransferase, NAD+ ADP-Ribosyltransferase, Mono(ADP-Ribose) Transferase, Mono ADPribose Transferases, Mono(ADPribosyl)transferase, NAD Agmatine ADP Ribosyltransferase, NAD(+)-L-arginine ADP-D-ribosyltransferase, ART Transferases, Mono ADP ribose Transferases, 0, Mono(ADP-Ribose) Transferases, NAD+ ADP Ribosyltransferase, EC 2.4.2.-, Mono ADP-ribose Transferases, ADPribose Transferase, Mono, NAD ADP Ribosyltransferase, ADPRT, Transferase, Mono ADPribose, Transferase, ADP Ribose, ARTase, Transferases, Mono ADPribose, NADP ADPRTase, NAD Arginine ADP Ribosyltransferase, Mono-ADP-Ribosyltransferase, ADP-ribose Transferases, Mono, NAD-Arginine ADP-Ribosyltransferase, ADP Ribose Transferases, NADP-ADPRTase, ADP-Ribosyltransferase, NAD-Arginine, ADP-Ribosyltransferase, NADP-Arginine, ADPribose Transferases, Mono, Mono(ADP-Ribosyl)transferase, NAD(P)(+)-Arginine ADP-Ribosyltransferase, ADP Ribosyltransferase, MonoADPribosyltransferase, NAD-Agmatine ADP-Ribosyltransferase, ADP-Ribosyltransferase, NAD+, Mono ADP Ribosyltransferase, Transferases, Mono ADP-ribose, Mono ADPribose Transferase, Transferases, ADP Ribose, Ribose Transferases, ADP
Instance information
2003; see NAD(P)(+)-ARGININE ADP-RIBOSYLTRANSFERASE 1992-2002, see NAD-ARGININE ADP-RIBOSYLTRANSFERASE 1989-1991; for NAD+ ADP-RIBOSYLTRANSFERASE see NAD+ ADP-RIBOSYLTRANSFERASE 1992-2002, see POLY ADP RIBOSE POLYMERASE 1988-1991; for MONO-ADP-RIBOSYLTRANSFERASE and NAD-ARGININE ADP-RIBOSYLTRANSFERASE and NADP-ARGININE ADP-RIBOSYLTRANSFERASE see NAD(P)(+)-ARGININE ADP-RIBOSYLTRANSFERASE 1992-2002, see NAD-ARGININE ADP-RIBOSYLTRANSFERASE 1989-1991 ,2003; for NAD+ ADP-RIBOSYLTRANSFERASE use POLY(ADP-RIBOSE) POLYMERASES 1988-2002
D036002