ATP Binding Cassette Transporter, Subfamily B, Member 1
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A 170-kDa transmembrane glycoprotein from the superfamily of ATP-BINDING CASSETTE TRANSPORTERS. It serves as an ATP-dependent efflux pump for a variety of chemicals, including many ANTINEOPLASTIC AGENTS. Overexpression of this glycoprotein is associated with multidrug resistance (see DRUG RESISTANCE, MULTIPLE).
Synonyms: PGY 1 Protein, P Glycoprotein, PGY-1 Protein, CD243 Antigen, ATP-Binding Cassette, Sub-Family B, Member 1, 0, ATP Binding Cassette Transporter, Subfamily B, Member 1, ABCB1 Protein, Multidrug Resistance Protein 1, MDR1 Protein, P-Glycoprotein, Antigen, CD243, ATP Binding Cassette Transporter, Sub-Family B, Member 1
Instance information
2019; see ATP-BINDING CASSETTE, SUB-FAMILY B, MEMBER 1 2018; see P-GLYCOPROTEIN 1995-2017; ATP BINDING CASSETTE TRANSPORTER, SUB-FAMILY B, MEMBER 1 was indexed under P-GLYCOPROTEIN 1995-1998; under CARRIER PROTEINS & MEMBRANE GLYCOPROTEINS 1980-1994; under GLYCOPROTEINS 1980-1987; and under MEMBRANE PROTEINS 1980-1982 ,note entry term: ATP BINDING CASSETTE TRANSPORTER, SUBFAMILY B is also available ,2019 (1995)
D020168