15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid
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A stable prostaglandin endoperoxide analog which serves as a thromboxane mimetic. Its actions include mimicking the hydro-osmotic effect of VASOPRESSIN and activation of TYPE C PHOSPHOLIPASES. (From J Pharmacol Exp Ther 1983;224(1): 108-117; Biochem J 1984;222(1):103-110)
Synonyms: 9,11-Dideoxy-11 alpha,9 alpha-epoxymethanoprostaglandin F2 alpha, (15S)-Hydroxy-11 alpha, 9 alpha-(epoxymethano)prosta-5Z, 13E-dienoic Acid, 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid, U46619, 76898-47-0, 9,11 epoxymethano PGH2, 9,11-epoxymethano-PGH2, U44619, 9,11-Dideoxy-11 alpha,9-alpha-epoxymethano-PGF2 alpha, (15S)hydroxy-9alpha,11alpha-(epoxymethano)prosta-5,13-dienoic acid, 5-Heptenoic Acid, 7-(6-(3-Hydroxy-1-Ocentyl)-2-Oxabicyclo(2.2.1)hept-5-yl)-, (1R-(1alpha,4alpha,5 beta(Z),6alpha(1E,3S*)))-, 0, 11 alpha,9 alpha Epoxymethano PGH2, U 44619, U 46619, U-46619, U-44619, 11 alpha,9 alpha-Epoxymethano PGH2
Instance information
1998; 15-HYDROXY-11 ALPHA,9 ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID was indexed under PROSTAGLANDIN ENDOPEROXIDES, SYNTHETIC 1978-97 & THROMBOXANE A2/analogs & derivatives 1983-97; (15S)HYDROXY-9ALPHA,11ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID and 9,11-EPOXYMETHANO-PGH2 were indexed under PROSTAGLANDINS H 1993-2003 & PROSTAGLANDIN ENDOPEROXIDES, SYNTHETIC 1986-1992 ,1998; use 15-HYDROXY-11 ALPHA,9 ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID (NM) 1977-1997; for (15S)HYDROXY-9ALPHA,11ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID and 9,11-EPOXYMETHANO-PGH2 use PROSTAGLANDIN H2 (NM) 1992-2003
D019796