A potent hepatotoxic and hepatocarcinogenic mycotoxin produced by the Aspergillus flavus group of fungi. It is also mutagenic, teratogenic, and causes immunosuppression in animals. It is found as a contaminant in peanuts, cottonseed meal, corn, and other grains. The mycotoxin requires epoxidation to aflatoxin B1 2,3-oxide for activation. Microsomal monooxygenases biotransform the toxin to the less toxic metabolites aflatoxin M1 and Q1.

Synonyms: Cyclopenta(c)furo(3',2':4,5)furo(2,3-h)(1)benzopyran-1,11-dione, 2,3,6a,9a-tetrahydro-4-methoxy-, (6aR-cis)-, Aflatoxin B1 Dihydrochloride, (6aR-cis)-Isomer, NSC-529592, 77076-87-0, Aflatoxin B, 77076-88-1, NSC 529592, 43043-21-6, Aflatoxin B1, cis(+,-)-Isomer, Aflatoxin B1, (6aR-cis)-Isomer, 2H-Labeled, Aflatoxin B1, (6aR-cis)-Isomer, 14C-Labeled, 10279-73-9, Aflatoxin B1, (6aR-cis)-Isomer, 3H-Labeled, 0, HSDB3453, 9N2N2Y55MH, HSDB 3453, Aflatoxin B(1), 84415-24-7, Aflatoxin B1, HSDB-3453, NSC529592