The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors.

Synonyms: 2-Amino-5-phosphonopentanoic Acid, 2-Amino-5-phosphonovaleric Acid, d-APV, dl-APV, 5 Phosphononorvaline, 0, 5-Phosphononorvaline, 2-Amino-5-phosphonopentanoate, 2 Amino 5 phosphonovalerate, Norvaline, 5-phosphono-, 76726-92-6, 2-APV, 2-Amino-5-phosphonovalerate, 2 Amino 5 phosphonovaleric Acid, 2 Amino 5 phosphonopentanoic Acid, 2 Amino 5 phosphonopentanoate