A group of enzymes that catalyze the reversible reduction-oxidation reaction of 20-hydroxysteroids, such as from a 20-ketosteroid to a 20-alpha-hydroxysteroid (EC 1.1.1.149) or to a 20-beta-hydroxysteroid (EC 1.1.1.53).

Synonyms: Dehydrogenases, 20-Hydroxysteroid, Dehydrogenases, 20 Hydroxysteroid, 20-Hydroxysteroid Dehydrogenases, EC 1.1.1.-, 20 Hydroxysteroid Dehydrogenases, Hydroxysteroid Dehydrogenases, 20