An enzyme that, in the presence of ATP and COENZYME A, catalyzes the cleavage of citrate to yield acetyl CoA, oxaloacetate, ADP, and ORTHOPHOSPHATE. This reaction represents an important step in fatty acid biosynthesis. This enzyme was formerly listed as EC 4.1.3.8.

Synonyms: Cleavage Enzyme, Citrate, ATP Citrate Lyase, Citrate Lyase, ATP, ATP Citrate Synthase, ATP Dependent Citrate Lyase, ATP-Dependent Citrate Lyase, ATP:citrate oxaloacetate-lyase ((pro-S)-CH2COO(-)--acetyl-CoA) (ATP-dephosphorylating), Citrate Cleavage Enzyme, Citrate Lyase, ATP-Dependent, ATP Citrate (pro-S)-Lyase, Lyase, ATP-Dependent Citrate, Synthase, ATP Citrate, ATP Citrate (pro-3S)-Lyase, EC 2.3.3.8, Citrate Synthase, ATP, Lyase, ATP Citrate