An enzyme of the transferase class that catalyzes condensation of the succinyl group from succinyl coenzyme A with glycine to form delta-aminolevulinate. It is a pyridoxyal phosphate protein and the reaction occurs in mitochondria as the first step of the heme biosynthetic pathway. The enzyme is a key regulatory enzyme in heme biosynthesis. In liver feedback is inhibited by heme. EC 2.3.1.37.

Synonyms: Synthetase, Aminolevulinic Acid, Synthase, delta-Aminolevulinate, delta Aminolevulinic Acid Synthetase, Synthase, 5-Aminolevulinate, Synthetase, delta-Aminolevulinic Acid, Synthetase, 5-Aminolevulinate, Aminolevulinic Acid Synthetase, EC 2.3.1.37, 5 Aminolevulinate Synthase, Succinyl-CoA:glycine C-Succinyltransferase (decarboxylating), delta-Aminolevulinic Acid Synthetase, 5-Aminolevulinate Synthase, 5-Aminolevulinate Synthetase, Acid Synthetase, delta-Aminolevulinic, Acid Synthetase, Aminolevulinic, 5 Aminolevulinate Synthetase, delta-Aminolevulinate Synthase, delta Aminolevulinate Synthase