A prodromal phase of infection with the human immunodeficiency virus (HIV). Laboratory criteria separating AIDS-related complex (ARC) from AIDS include elevated or hyperactive B-cell humoral immune responses, compared to depressed or normal antibody reactivity in AIDS; follicular or mixed hyperplasia in ARC lymph nodes, leading to lymphocyte degeneration and depletion more typical of AIDS; evolving succession of histopathological lesions such as localization of Kaposi's sarcoma, signaling the transition to the full-blown AIDS.

Synonyms: ARC, Lymphadenopathy Syndrome, AIDS Related Complex, Syndromes, Lymphadenopathy, Complex, AIDS-Related, AIDS-Related Complex, Lymphadenopathy Syndromes, Syndrome, Lymphadenopathy