A group of inherited disorders of the ADRENAL GLANDS, caused by enzyme defects in the synthesis of cortisol (HYDROCORTISONE) and/or ALDOSTERONE leading to accumulation of precursors for ANDROGENS. Depending on the hormone imbalance, congenital adrenal hyperplasia can be classified as salt-wasting, hypertensive, virilizing, or feminizing. Defects in STEROID 21-HYDROXYLASE; STEROID 11-BETA-HYDROXYLASE; STEROID 17-ALPHA-HYDROXYLASE; 3-beta-hydroxysteroid dehydrogenase (3-HYDROXYSTEROID DEHYDROGENASES); TESTOSTERONE 5-ALPHA-REDUCTASE; or steroidogenic acute regulatory protein; among others, underlie these disorders.

Synonyms: Congenital Adrenal Hyperplasias, Adrenal Hyperplasias, Congenital, Hyperplasias, Congenital Adrenal, Congenital Adrenal Hyperplasia, Adrenal Hyperplasia, Congenital, Hyperplasia, Congenital Adrenal

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use ADRENAL HYPERPLASIA, CONGENITAL to search ADRENOGENITAL SYNDROME 1966-79 ,80; was ADRENOGENITAL SYNDROME 1963-79

identifier

D000312