A syndrome characterized by a TONIC PUPIL that occurs in combination with decreased lower extremity reflexes. The affected pupil will respond more briskly to accommodation than to light (light-near dissociation) and is supersensitive to dilute pilocarpine eye drops, which induce pupillary constriction. Pathologic features include degeneration of the ciliary ganglion and postganglionic parasympathetic fibers that innervate the pupillary constrictor muscle. (From Adams et al., Principles of Neurology, 6th ed, p279)

Synonyms: Holmes-Adie Syndrome, Pupils, Poorly Reacting, Pupil, Poorly Reacting, Poorly Reacting Pupil, Adie's Syndrome, Syndrome, Holmes-Adie, Syndrome, Adie, Poorly Reacting Pupils, Syndrome, Adie's, Adie Syndrome, Holmes Adie Syndrome

Instance information

comment

2000; see ADIE'S SYNDROME 1963-1999 ,2000 (1963)

identifier

D000270