A carboxylating enzyme that catalyzes the conversion of ATP, acetyl-CoA, and HCO3- to ADP, orthophosphate, and malonyl-CoA. It is a biotinyl-protein that also catalyzes transcarboxylation. The plant enzyme also carboxylates propanoyl-CoA and butanoyl-CoA (From Enzyme Nomenclature, 1992) EC 6.4.1.2.

Synonyms: Acetyl CoA Carboxylase, Carboxylase, Acetyl-CoA, Acetyl-CoA:carbon-dioxide ligase (ADP-forming), Acetyl Coenzyme A Carboxylase, EC 6.4.1.2, Acetyl-CoA Carboxylase