ATP Binding Cassette Transporter, Subfamily A

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A large, highly conserved, subfamily of ATP binding cassette transporters structurally characterized by a membrane-spanning domain composed of six ALPHA-HELICES, a large extracellular loop, nucleotide-binding domain, and a conserved cytoplasmic 80 amino acid sequence. In humans, it includes ABCA1(ATP BINDING CASSETTE TRANSPORTER 1) through ABCA10, as well as ABCA12 and ABCA13.

Synonyms: ATP Binding Cassette Transporter, Subfamily A, 0, ABCA Transporters, ATP Binding Cassette Transporter, Sub Family A, Transporters, ABCA, ATP Binding Cassette Transporter, Sub-Family A

Instance information

comment

2019; see ATP BINDING CASSETTE TRANSPORTER, SUB-FAMILY A 2018 ,2019 (2018)

identifier

D000073874