A disintegrin and metalloproteinase domain-containing protein that is expressed as two alternatively-spliced forms: a long transmembrane form (ADAM12-L) and a short soluble form (ADAM12-S). It modulates the cleavage of INSULIN-LIKE GROWTH FACTOR BINDING PROTEINS and may also regulate CELL FUSION during MYOGENESIS.

Synonyms: ADAM12 S Protein, Disintegrin and Metalloproteinase Domain-Containing Protein 12, ADAM-12 Protein, 0, ADAM12-L Protein, ADAM12 Protein, Disintegrin and Metalloproteinase Domain Containing Protein 12, Meltrin alpha Protein, ADAM12 L Protein, EC 3.4.24.-, Meltrin-alpha Protein, ADAM12-S Protein, ADAM 12 Protein

Instance information

comment

2017 (1997) ,2017; ADAM12 PROTEIN was indexed under MEMBRANE PROTEINS and ADAM PROTEINS 2006-2016; and under METALLOENDOPEPTIDASES 1997-2005

identifier

D000072199

Instance relations