A subfamily of ADAM proteases that are distinguished by the presence of one or more THROMBOSPONDIN type-1 repeats (TSRs). These are three-strand motifs that contain characteristic TRYPTOPHAN, ARGININE, and CYSTEINE residues respectively. In contrast to ADAM proteins, which reside on CELL MEMBRANES, ADAMTS proteases are secreted and function in the EXTRACELLULAR MATRIX.

A subfamily of ADAMTS proteins that lack a protease domain.

Synonyms: Protein, ADAMTSL, ADAMTS-Like Proteins, ADAMTSL Proteins, Protease, ADAMTS, Adam Metallopeptidases With Thrombospondin Type 1 Motif Proteins, Protein, ADAMTS-Like, Protein, ADAMTS, ADAMTS Protein, A Disintegrin And Metalloproteinase With Thrombospondin Motifs Proteins, Adam Metallopeptidases With Thrombospondin Type 1 Motif Protein, ADAMTSL Protein, 0, ADAMTS Like Proteins, ADAMTS Like Protein, A Disintegrin And Metalloproteinase With Thrombospondin Motifs Protein, EC 3.4.24.-, ADAMTS Proteases, ADAMTS Proteins, ADAMTS-Like Protein, ADAMTS Protease

Instance information

comment

2017

identifier

D000071096