A fusion protein immunoconjugate of the extracellular domain of CTLA4 and the Fc domain of human IgG1. It functions as a T-cell co-stimulation blocker that inhibits TNF-ALPHA and prevents the activation of T-LYMPHOCYTES. It is used in the treatment of RHEUMATOID ARTHRITIS.

Synonyms: BMS-188667, BMS 188667, CTLA4 Ig Immunoconjugate, Belatacept, CTLA4-Fc, CTLA4-Ig, 7D0YB67S97, Cytotoxic T Lymphocyte Associated Antigen 4 Immunoglobulin, LEA29Y, 0, CTLA4-Ig Immunoconjugate, Cytotoxic T Lymphocyte-Associated Antigen 4-Immunoglobulin, Abatacept, Orencia, BMS-224818, BMS 224818, BMS224818, Nulojix, Immunoconjugate, CTLA4-Ig, CTLA-4-Ig, BMS188667

Instance information

comment

2016; ABATACEPT was indexed under IMMUNOCONJUGATES 2002-2015 ,2016 (2002)

identifier

D000069594

Instance relations